Michael  Abdelsayed

Michael Abdelsayed, Ph.D.

Assistant Professor of Biology, Biochemistry Coordinator

(805) 493-3367
SSC 204


Dr. Abdelsayed is a biochemist interested in the discovery of functional nucleic acids. He received his Ph.D. from University of California, Irvine in biological sciences. His research utilizes biochemistry and molecular biology techniques to discover and engineer novel functional RNA molecules. He is interested in discovering what roles these RNA molecules play in regulating gene expression. His research also includes evolving synthetic RNAs for therapeutic and diagnostic purposes.

Dr. Abdelsayed is excited to teach Biochemistry and Genomics, in addition to other biology courses. He is passionate about sharing his enthusiasm for science through teaching and participating in outreach events. Outside of academia, he enjoys going to concerts and having dance parties at home with his two young boys and wife.


Dr. Abdelsayed is leaving CLU in the summer of 2024.


California State University, Channel Islands

B.S. in Chemistry in 2008


University of California, Irvine

Ph.D. in Biological Sciences in 2016


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Robo-Therm, a pipeline to RNA Thermometer discovery and validation. 

Sharts DM, Almanza MT, Banks AV, Castellanos AM, O Hernandez CG, Lopez ML, Rodriguez D, Tong AY, Segeberg MR, M Passalacqua LF, Abdelsayed MM. RNA. 2024 Apr 2:rna.079980.124. doi: 10.1261/rna.079980.124. Epub ahead of print. PMID: 38565243.


Characterization of a FourU RNA Thermometer in the 5′ Untranslated Region of Autolysin Gene blyA in the Bacillus subtilis 168 Prophage SPβ

Alina Y. Tong, Emma E. Caudill, Alexis R. Jones, Luiz F. M. Passalacqua, and Michael M. Abdelsayed Biochemistry Article ASAP
DOI: 10.1021/acs.biochem.3c00368

Regulation of mRNA translation by a photoriboswitch
Kelly A. Rotstan†, Michael M. Abdelsayed†, Luiz F. M. Passalacqua, Fabio Chizzolini, Kasireddy Sudarshan, A. Richard Chamberlin, Jiří Míšek, & Andrej Lupták
eLife Sciences 2020 9:e51737
eLife 2020;9:e51737 DOI: 10.7554/eLife.51737

Multiplex Aptamer Discovery through Apta-Seq and Its Application to ATP Aptamers Derived from Human-Genomic SELEX
Michael M. Abdelsayed, Bao T. Ho, Michael M. K. Vu, Julio Polanco, Robert C. Spitale, and Andrej Lupták
ACS Chemical Biology 2017 12 (8), 2149-2156
DOI: 10.1021/acschembio.7b00001